There is no medicine available that will treat canker sores. Generally, even without medicine to treat canker sores they heal within 2 weeks. But during that time, canker sores can tingle or burn making eating, drinking, even talking uncomfortable or painful. Although there is no cure yet, there are canker sore herbal remedies that can alleviate the pain and irritation associated with canker sores. There can help reduce the pain and discomfort of canker sores and speed the natural healing process by cleansing the mouth and reducing irritation.